2. Signaling Pathways
  3. GPCR/G Protein
  4. Protease Activated Receptor (PAR)
  5. Protease Activated Receptor (PAR) Isoform
  6. Protease Activated Receptor (PAR) Agonist

Protease Activated Receptor (PAR) Agonist

Protease Activated Receptor (PAR) Agonists (8):

Cat. No. Product Name Effect Purity
  • HY-P4803
    PAR-2 (1-6) (human)
    		Agonist 99.49%
    PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist.
  • HY-P2519A
    Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
    		Agonist 99.86%
    Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide.
  • HY-14351
    AC-264613
    		Agonist 98.3%
    AC-264613 is a potent and selective protease-activated receptor (PAR-2) agonist with a pEC50 of 7.5.
  • HY-P5360
    TFLLRN-NH2
    		Agonist 99.34%
    TFLLRN-NH2 is a biological active peptide. (PAR-1 Agonist)
  • HY-P2519
    Protease-Activated Receptor-3 (PAR-3) (1-6), human
    		Agonist
    Protease-Activated Receptor-3 (PAR-3) (1-6), human is a proteinase-activated receptor (PAR-3) agonist peptide.
  • HY-P5372
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
    		Agonist
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)
  • HY-P5358
    YFLLRNP
    		Agonist
    YFLLRNP is a biological active peptide. (a partial agonist of PAR-1. YFLLRNP selectively active G12/13 signaling pathway without activating Gq or Gi pathways at low concentrations. YFLLRNP (60 μM))
  • HY-P1313
    PAR 4 (1-6) (human)
    		Agonist
    PAR 4 (1-6) human, a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist.